H+ [Ligand Id: 2346] activity data from GtoPdb

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  • Kir1.1 in Rat [GtoPdb: 429] [UniProtKB: P35560]
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  • Kir2.3 in Human [GtoPdb: 432] [UniProtKB: P48050]
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  • Kir2.4 in Human [GtoPdb: 433] [UniProtKB: Q9UNX9]
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  • Kir4.1 in Rat [GtoPdb: 438] [UniProtKB: P49655]
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  • Kir4.2 in Rat [GtoPdb: 439] [UniProtKB: Q91ZF1]
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  • TRPM5 in Human [GtoPdb: 497] [UniProtKB: Q9NZQ8]
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  • TRPV1 in Human [GtoPdb: 507] [UniProtKB: Q8NER1]
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  • ZAC in Human [GtoPdb: 587] [UniProtKB: Q401N2]
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  • ASIC1 in Human [GtoPdb: 684] [UniProtKB: P78348]
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  • ASIC2 in Human [GtoPdb: 685] [UniProtKB: Q16515]
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  • ASIC3 in Human [GtoPdb: 686] [UniProtKB: Q9UHC3]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Kir1.1 in Rat [GtoPdb: 429] [UniProtKB: P35560]
GtoPdb - - 6.8 pIC50 - - - J. Biol. Chem. (1996) 271: 17261-6 [PMID:8663367];
Am. J. Physiol. (1995) 268: C1173-8 [PMID:7762610];
Biophys. J. (2003) 84: 910-21 [PMID:12547773]
Kir2.3 in Human [GtoPdb: 432] [UniProtKB: P48050]
GtoPdb - - 6.77 pKi - - - J. Physiol. (Lond.) (1999) 516 ( Pt 3): 699-710 [PMID:10200419];
J. Biol. Chem. (2000) 275: 31573-80 [PMID:10896660]
GtoPdb - - 7.4 pKi - - - Neuron (1995) 15: 1157-68 [PMID:7576658];
J. Physiol. (Lond.) (1999) 516 ( Pt 3): 699-710 [PMID:10200419]
Kir2.4 in Human [GtoPdb: 433] [UniProtKB: Q9UNX9]
GtoPdb - - 7.14 pKi - - - Am. J. Physiol., Cell Physiol. (2000) 279: C771-84 [PMID:10942728]
Kir4.1 in Rat [GtoPdb: 438] [UniProtKB: P49655]
GtoPdb - - 6.1 pEC50 - - - J. Physiol. (Lond.) (2001) 532: 359-67 [PMID:11306656];
J. Biol. Chem. (2000) 275: 16404-7 [PMID:10764726]
Kir4.2 in Rat [GtoPdb: 439] [UniProtKB: Q91ZF1]
GtoPdb - - 7.1 pEC50 - - - J. Physiol. (Lond.) (2001) 532: 359-67 [PMID:11306656]
TRPM5 in Human [GtoPdb: 497] [UniProtKB: Q9NZQ8]
GtoPdb - - 3.2 pIC50 630000 nM IC50
TRPV1 in Human [GtoPdb: 507] [UniProtKB: Q8NER1]
GtoPdb - - 5.4 pEC50 3980 nM EC50
ZAC in Human [GtoPdb: 587] [UniProtKB: Q401N2]
GtoPdb - - 5.6 pEC50 - - - Biochem. Pharmacol. (2016) 103: 109-17 [PMID:26872532]
ASIC1 in Human [GtoPdb: 684] [UniProtKB: P78348]
GtoPdb - - 6.2 pEC50 ~630 nM EC50
GtoPdb - - 6.8 pEC50 ~160 nM EC50
ASIC2 in Human [GtoPdb: 685] [UniProtKB: Q16515]
GtoPdb - - 5 pEC50 ~10000 nM EC50
ASIC3 in Human [GtoPdb: 686] [UniProtKB: Q9UHC3]
GtoPdb - - 4.3 pEC50 ~50000 nM EC50
GtoPdb - - 6.7 pEC50 ~200 nM EC50

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.