von Willebrand factor   

GtoPdb Ligand ID: 6755

Synonyms: Vonvendi® | vWF
von Willebrand factor is an approved drug (FDA (2015))
Comment: Details of the structure of von Willebrand factor (vWF) are available in its UniProt record. The pre-pro peptide is 2813 amino acids, with residues 1-22 being the signal peptide, residues 23-763 forming von Willebrand antigen 2, and the remaining 2050 residues (764-2813) constituting vWF. The Uniprot record also provides details of mutations underlying defective vWF activity in the three subtypes of von Willebrand disease.
Species: Human
Classification
Compound class Endogenous peptide in human, mouse or rat
Approved drug? Yes (FDA (2015))
Synonyms
Vonvendi® | vWF
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
VWF von Willebrand factor Human von Willebrand factor F8VWF
Database Links
CATH/Gene3D 3.40.50.410
DrugBank Target P04275 (Hs)
Ensembl Gene ENSG00000110799 (Hs)
Entrez Gene 7450 (Hs)
GtoPdb PubChem SID 178103366
Human Protein Atlas ENSG00000110799 (Hs)
Immunopaedia Search von Willebrand factor
UniProtKB P04275 (Hs)
Wikipedia Von_Willebrand_factor