ChEMBL ligand: CHEMBL415284 (Nalorphine, Nalorphine serb)
δ receptor/Delta opioid receptor in Human [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143] There should be some charts here, you may need to enable JavaScript!
κ receptor/Kappa opioid receptor in Human [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145] Kappa opioid receptor in Guinea pig [ChEMBL: CHEMBL3952] [UniProtKB: P41144] There should be some charts here, you may need to enable JavaScript!
μ receptor/Mu opioid receptor in Human [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372] μ receptor/Mu opioid receptor in Rat [ChEMBL: CHEMBL270] [GtoPdb: 319] [UniProtKB: P33535] There should be some charts here, you may need to enable JavaScript!
sigma non-opioid intracellular receptor 1/Sigma opioid receptor in Human [ChEMBL: CHEMBL287] [GtoPdb: 2552] [UniProtKB: Q99720] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
δ receptor/Delta opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143]
ChEMBL	Displacement of [3H]Naltrindole form human delta opioid receptor expressed in CHO cells	B	6.92	pKi	120	nM	Ki	Bioorg Med Chem Lett (2009) 19: 203-208 [PMID:19027293]
GtoPdb	-	-	7.4	pKi	-	-	-	NIDA Res Monogr (1998) 178: 440-66 [PMID:9686407]
κ receptor/Kappa opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145]
ChEMBL	Binding affinity to human kappa opioid receptor	B	8.7	pKi	2	nM	Ki	J Med Chem (2016) 59: 810-840 [PMID:26390077]
GtoPdb	-	-	9.1	pKi	-	-	-	NIDA Res Monogr (1998) 178: 440-66 [PMID:9686407]; J Pharmacol Exp Ther (1997) 282: 676-84 [PMID:9262330]
ChEMBL	Displacement of [3H]U69593 form human kappa opioid receptor expressed in CHO cells	B	9.42	pKi	0.38	nM	Ki	Bioorg Med Chem Lett (2009) 19: 203-208 [PMID:19027293]
Kappa opioid receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3952] [UniProtKB: P41144]
ChEMBL	Binding affinity to Opioid receptor kappa 1 in guinea pig cortex using [3H]EKC as radioligand	B	7.82	pKi	15	nM	Ki	J Med Chem (1988) 31: 555-560 [PMID:2831363]
μ receptor/Mu opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372]
GtoPdb	-	-	8.9	pKi	-	-	-	NIDA Res Monogr (1998) 178: 440-66 [PMID:9686407]
ChEMBL	Binding affinity to human mu opioid receptor	B	9.44	pKi	0.36	nM	Ki	J Med Chem (2016) 59: 810-840 [PMID:26390077]
ChEMBL	Displacement of [3H]DAMGO form human mu opioid receptor expressed in CHO cells	B	9.72	pKi	0.19	nM	Ki	Bioorg Med Chem Lett (2009) 19: 203-208 [PMID:19027293]
μ receptor/Mu opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL270] [GtoPdb: 319] [UniProtKB: P33535]
ChEMBL	Binding affinity to Opioid receptor mu 1 in rat brain using [3H]-NAL as radioligand	B	8.19	pKi	6.5	nM	Ki	J Med Chem (1988) 31: 555-560 [PMID:2831363]
sigma non-opioid intracellular receptor 1/Sigma opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL287] [GtoPdb: 2552] [UniProtKB: Q99720]
ChEMBL	Inhibition of specific binding of [125I]-PIPAG to sigma binding site in Guinea pig brain membranes	B	5.3	pIC50	5000	nM	IC50	J Med Chem (1992) 35: 4683-4689 [PMID:1469697]
ChEMBL	Inhibition of specific binding of [3H]DTG to sigma binding site in Guinea pig brain membranes	B	5.4	pIC50	4000	nM	IC50	J Med Chem (1992) 35: 4683-4689 [PMID:1469697]
ChEMBL	Inhibition of specific binding of [3H]3-PPP to sigma binding site in Guinea pig brain membranes	B	5.55	pIC50	2850	nM	IC50	J Med Chem (1992) 35: 4683-4689 [PMID:1469697]
ChEMBL	Inhibition of specific binding of [3H]NANM of sigma binding site in Guinea pig brain membranes	B	5.74	pIC50	1800	nM	IC50	J Med Chem (1992) 35: 4683-4689 [PMID:1469697]
ChEMBL	Inhibition of specific binding of [125I]PIPAG to sigma receptor in Guinea pig brain membranes	B	6.13	pIC50	735	nM	IC50	J Med Chem (1992) 35: 4683-4689 [PMID:1469697]
ChEMBL	Inhibition of specific binding of [3H]DTG to sigma receptor in Guinea pig brain membranes	B	6.2	pIC50	625	nM	IC50	J Med Chem (1992) 35: 4683-4689 [PMID:1469697]
ChEMBL	Inhibition of specific binding of [3H]3-PPP to sigma receptor in Guinea pig brain membranes	B	7.03	pIC50	93	nM	IC50	J Med Chem (1992) 35: 4683-4689 [PMID:1469697]
ChEMBL	Inhibition of specific binding of [3H]NANM of sigma receptor in Guinea pig brain membranes	B	7.32	pIC50	48	nM	IC50	J Med Chem (1992) 35: 4683-4689 [PMID:1469697]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]