ChEMBL ligand: CHEMBL548
DP1 receptor in Human [GtoPdb: 338] [UniProtKB: Q13258] There should be some charts here, you may need to enable JavaScript!
DP2 receptor in Human [GtoPdb: 339] [UniProtKB: Q9Y5Y4] DP2 receptor in Mouse [GtoPdb: 339] [UniProtKB: Q9Z2J6] There should be some charts here, you may need to enable JavaScript!
EP1 receptor in Human [GtoPdb: 340] [UniProtKB: P34995] EP1 receptor in Mouse [GtoPdb: 340] [UniProtKB: P35375] EP1 receptor in Rat [GtoPdb: 340] [UniProtKB: P70597] There should be some charts here, you may need to enable JavaScript!
EP2 receptor in Human [GtoPdb: 341] [UniProtKB: P43116] EP2 receptor in Mouse [GtoPdb: 341] [UniProtKB: Q62053] EP2 receptor in Rat [GtoPdb: 341] [UniProtKB: Q62928] There should be some charts here, you may need to enable JavaScript!
EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115] EP3 receptor in Mouse [GtoPdb: 342] [UniProtKB: P30557] EP3 receptor in Rat [GtoPdb: 342] [UniProtKB: P34980] There should be some charts here, you may need to enable JavaScript!
EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408] EP4 receptor in Mouse [GtoPdb: 343] [UniProtKB: P32240] EP4 receptor in Rat [GtoPdb: 343] [UniProtKB: P43114] There should be some charts here, you may need to enable JavaScript!
FP receptor in Human [GtoPdb: 344] [UniProtKB: P43088] FP receptor in Mouse [GtoPdb: 344] [UniProtKB: P43117] There should be some charts here, you may need to enable JavaScript!
TP receptor in Human [GtoPdb: 346] [UniProtKB: P21731] There should be some charts here, you may need to enable JavaScript!
CatSper1 in Human [GtoPdb: 388] [UniProtKB: Q8NEC5] There should be some charts here, you may need to enable JavaScript!
CatSper2 in Human [GtoPdb: 389] [UniProtKB: Q96P56] There should be some charts here, you may need to enable JavaScript!
CatSper3 in Human [GtoPdb: 390] [UniProtKB: Q86XQ3] There should be some charts here, you may need to enable JavaScript!
CatSper4 in Human [GtoPdb: 391] [UniProtKB: Q7RTX7] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
DP1 receptor in Human [GtoPdb: 338] [UniProtKB: Q13258]
GtoPdb	-	-	7	pKi	-	-	-	J Biol Chem (1995) 270: 18910-6 [PMID:7642548]; Br J Pharmacol (1998) 123: 1317-24 [PMID:9579725]; Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
DP2 receptor in Human [GtoPdb: 339] [UniProtKB: Q9Y5Y4]
GtoPdb	-	-	5.3	pKi	-	-	-	Br J Pharmacol (2002) 137: 1163-72 [PMID:12466225]
DP2 receptor in Mouse [GtoPdb: 339] [UniProtKB: Q9Z2J6]
GtoPdb	-	-	5.5	pKi	-	-	-	J Pharmacol Exp Ther (2003) 306: 463-70 [PMID:12721327]
EP1 receptor in Human [GtoPdb: 340] [UniProtKB: P34995]
GtoPdb	-	-	8	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP1 receptor in Mouse [GtoPdb: 340] [UniProtKB: P35375]
GtoPdb	-	-	7.7	pKi	-	-	-	Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]; Endocrinology (2000) 141: 1554-9 [PMID:10746663]
EP1 receptor in Rat [GtoPdb: 340] [UniProtKB: P70597]
GtoPdb	-	-	7.7	pKi	-	-	-	Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]
EP2 receptor in Human [GtoPdb: 341] [UniProtKB: P43116]
GtoPdb	-	-	8.3	pKi	5.01	nM	Ki	Br J Pharmacol (2006) 148: 326-39 [PMID:16604093]; Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]; Mol Pharmacol (1999) 56: 545-51 [PMID:10462542]
EP2 receptor in Mouse [GtoPdb: 341] [UniProtKB: Q62053]
GtoPdb	-	-	7.9	pKi	-	-	-	Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]; Endocrinology (2000) 141: 1554-9 [PMID:10746663]; Life Sci (2003) 74: 135-41 [PMID:14607240]
EP2 receptor in Rat [GtoPdb: 341] [UniProtKB: Q62928]
GtoPdb	-	-	8.2	pKi	-	-	-	Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]
EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115]
GtoPdb	-	-	8.68	pKd	2.1	nM	Kd	Am J Physiol Renal Physiol (2008) 295: F984-94 [PMID:18632791]
GtoPdb	-	-	9.1	pKd	0.8	nM	Kd	Br J Pharmacol (2006) 148: 326-39 [PMID:16604093]; Biochem Pharmacol (2012) 84: 68-75 [PMID:22480736]; Am J Physiol Renal Physiol (2008) 295: F984-94 [PMID:18632791]
GtoPdb	-	-	9.48	pKi	0.33	nM	Ki	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP3 receptor in Mouse [GtoPdb: 342] [UniProtKB: P30557]
GtoPdb	-	-	8.85	pKd	1.4	nM	Kd	Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
GtoPdb	-	-	9.07	pKi	0.85	nM	Ki	Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
EP3 receptor in Rat [GtoPdb: 342] [UniProtKB: P34980]
GtoPdb	-	-	8.41	pKd	3.9	nM	Kd	FEBS Lett (1994) 351: 119-22 [PMID:8076679]; Br J Pharmacol (2005) 145: 1132-42 [PMID:15937517]
GtoPdb	-	-	8.96	pKd	1.1	nM	Kd	Am J Physiol Renal Physiol (2008) 295: F984-94 [PMID:18632791]
GtoPdb	-	-	9.1	pKd	0.8	nM	Kd	Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]; Br J Pharmacol (2005) 145: 1132-42 [PMID:15937517]; Am J Physiol Renal Physiol (2008) 295: F984-94 [PMID:18632791]
GtoPdb	-	-	9	pKi	-	-	-	Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]
GtoPdb	-	-	9.39	pEC50	0.41	nM	EC50	Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]
EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408]
GtoPdb	-	-	9.1	pKi	0.79	nM	Ki	Br J Pharmacol (2006) 148: 326-39 [PMID:16604093]; Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]; Mol Pharmacol (1999) 56: 545-51 [PMID:10462542]; Br J Pharmacol (2000) 130: 1919-1926 [PMID:10952683]; J Pharmacol Exp Ther (2007) 322: 686-94 [PMID:17495127]
GtoPdb	-	-	6.05	pEC50	900	nM	EC50	J Pharmacol Exp Ther (2009) 331: 297-307 [PMID:19584306]
EP4 receptor in Mouse [GtoPdb: 343] [UniProtKB: P32240]
GtoPdb	-	-	8.6	pKd	2.5	nM	Kd	Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
GtoPdb	-	-	8.7	pKi	2	nM	Ki	Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]; Endocrinology (2000) 141: 1554-9 [PMID:10746663]
EP4 receptor in Rat [GtoPdb: 343] [UniProtKB: P43114]
GtoPdb	-	-	9	pKi	-	-	-	Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]
FP receptor in Human [GtoPdb: 344] [UniProtKB: P43088]
GtoPdb	-	-	6.9	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]; Biochem J (2003) 371: 443-9 [PMID:12519077]
FP receptor in Mouse [GtoPdb: 344] [UniProtKB: P43117]
GtoPdb	-	-	7	pKi	-	-	-	Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
TP receptor in Human [GtoPdb: 346] [UniProtKB: P21731]
GtoPdb	-	-	4.5	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
CatSper1 in Human [GtoPdb: 388] [UniProtKB: Q8NEC5]
GtoPdb	Patch clamp electrophysiology	-	6.3	pEC50	500	nM	EC50	Nature (2011) 471: 387-91 [PMID:21412339]
CatSper2 in Human [GtoPdb: 389] [UniProtKB: Q96P56]
GtoPdb	Patch clamp electrophysiology.	-	6.3	pEC50	500	nM	EC50	Nature (2011) 471: 387-91 [PMID:21412339]
CatSper3 in Human [GtoPdb: 390] [UniProtKB: Q86XQ3]
GtoPdb	Patch clamp electrophysiology.	-	6.3	pEC50	500	nM	EC50	Nature (2011) 471: 387-91 [PMID:21412339]
CatSper4 in Human [GtoPdb: 391] [UniProtKB: Q7RTX7]
GtoPdb	Patch clamp electrophysiology.	-	6.3	pEC50	500	nM	EC50	Nature (2011) 471: 387-91 [PMID:21412339]

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]