D-galactose [Ligand Id: 4646] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1233058 (Galactose)
  • PA-I galactophilic lectin in Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) [ChEMBL: CHEMBL3351196] [UniProtKB: Q05097]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
PA-I galactophilic lectin in Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3351196] [UniProtKB: Q05097]
ChEMBL Binding affinity to Pseudomonas aeruginosa LecA assessed as change in enthalpy B 4.06 pKd 88000 nM Kd Bioorg Med Chem Lett (2023) 90: 129322-129322 [PMID:37182609]
ChEMBL Binding affinity to Pseudomonas aeruginosa LecA assessed as change in entropy B 4.06 pKd 88000 nM Kd Bioorg Med Chem Lett (2023) 90: 129322-129322 [PMID:37182609]
ChEMBL Binding affinity to Pseudomonas aeruginosa LecA assessed as dissociation constant B 4.06 pKd 88000 nM Kd Bioorg Med Chem Lett (2023) 90: 129322-129322 [PMID:37182609]
ChEMBL Binding affinity to Pseudomonas aeruginosa PAO1 LecA assessed as dissociation constant B 4.06 pKd 87500 nM Kd J Med Chem (2016) 59: 5929-5969 [PMID:26804741]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]