Sch.336 [Ligand Id: 9799] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL180465 |
|---|
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CB1 receptor/Cannabinoid CB1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554] | ||||||||
| GtoPdb | - | - | 6.04 | pKi | 905 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 783-6 [PMID:15664857] |
| ChEMBL | Binding affinity for cannabinoid receptor 1 | B | 6.04 | pKi | 905 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 783-786 [PMID:15664857] |
| GtoPdb | - | - | 6.7 | pEC50 | 200 | nM | EC50 | J Pharmacol Exp Ther (2006) 316: 780-8 [PMID:16258021] |
| CB2 receptor/Cannabinoid CB2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972] | ||||||||
| GtoPdb | Measuring competitin binding with [3H]CP55,940 for binding to human CB2 on Sf9 cell membranes. | - | 8.74 | pKi | 1.8 | nM | Ki | J Pharmacol Exp Ther (2006) 316: 780-8 [PMID:16258021] |
| ChEMBL | Inhibition constant against Cannabinoid receptor 2 | B | 9.4 | pKi | 0.4 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 4417-4420 [PMID:16115769] |
| GtoPdb | - | - | 9.4 | pKi | 0.4 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 783-6 [PMID:15664857] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
