BMY 22089 [Ligand Id: 2973] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL2367463 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| hydroxymethylglutaryl-CoA synthase 1/HMG-CoA synthase in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2189] [GtoPdb: 638] [UniProtKB: P17425] | ||||||||
| ChEMBL | In vitro inhibition of rat liver microsomal HMG-CoA reductase activity | B | 7.72 | pIC50 | 19 | nM | IC50 | J Med Chem (1989) 32: 2038-2041 [PMID:2769677] |
| hydroxymethylglutaryl-CoA reductase in Rat [GtoPdb: 639] [UniProtKB: P51639] | ||||||||
| GtoPdb | In vitro inhibition of HMG-CoA reductase | - | 7.62 | pIC50 | 24 | nM | IC50 | J Med Chem (1990) 33: 2982-99 [PMID:2231596] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
