ME0328 [Ligand Id: 8468] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL3092537 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| poly(ADP-ribose) polymerase 1/Poly [ADP-ribose] polymerase-1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3105] [GtoPdb: 2771] [UniProtKB: P09874] | ||||||||
| GtoPdb | - | - | 5.2 | pIC50 | 6300 | nM | IC50 | J Med Chem (2013) 56: 9556-68 [PMID:24188023] |
| ChEMBL | Inhibition of full length ATRD1 (unknown origin) | B | 5.2 | pIC50 | 6300 | nM | IC50 | J Med Chem (2013) 56: 9556-9568 [PMID:24188023] |
| ChEMBL | Inhibition of catalytic domain of ATRD1 (unknown origin) | B | 5.43 | pIC50 | 3700 | nM | IC50 | J Med Chem (2013) 56: 9556-9568 [PMID:24188023] |
| poly (ADP-ribose) polymerase 3/Poly [ADP-ribose] polymerase 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5083] [GtoPdb: 2864] [UniProtKB: Q9Y6F1] | ||||||||
| ChEMBL | Inhibition of full length ATRD3 (unknown origin) | B | 6.05 | pIC50 | 900 | nM | IC50 | J Med Chem (2013) 56: 9556-9568 [PMID:24188023] |
| GtoPdb | - | - | 6.05 | pIC50 | 900 | nM | IC50 | J Med Chem (2013) 56: 9556-68 [PMID:24188023] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
