clascoterone [Ligand Id: 11215] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL3590187 (Breezula, Cb-03-01, CB-03-01, Clascoterone, Cortexolone 17.alpha.-propionate, Cortodoxone 17.alpha.-propionate, Winlevi) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| Androgen receptor/Androgen Receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1871] [GtoPdb: 628] [UniProtKB: P10275] | ||||||||
| ChEMBL | Displacement of [3H]methyltrienolone from androgen receptor in human prostate cancer cells | B | 7.4 | pKi | 40 | nM | Ki | Medchemcomm (2014) 5: 904-914 |
| GtoPdb | Determined by measuring displacement of [3H]methyltrienolone from androgen receptor in human prostate cancer cells. | - | 7.4 | pKi | 40 | nM | Ki | MedChemComm (2014) 5: 904-914 |
| ChEMBL | Displacement of [3H]methyltrienolone from androgen receptor in human prostate cancer cells | B | 7.3 | pIC50 | 50 | nM | IC50 | Medchemcomm (2014) 5: 904-914 |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
