midazolam   Click here for help

GtoPdb Ligand ID: 3342

Synonyms: Buccolam® | Dormicum® | Nayzilam® | USL261 (nasal spray formulation) [1] | Versed®
Approved drug PDB Ligand
midazolam is an approved drug (FDA (2000), EMA (2011))
Compound class: Synthetic organic
Comment: Midazolam is a benzodiazepine class sedative drug.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 29.66
Molecular weight 325.08
XLogP 4.57
No. Lipinski's rules broken 0
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Canonical SMILES Clc1ccc2c(c1)C(=NCc1n2c(C)nc1)c1ccccc1F
Isomeric SMILES Clc1ccc2c(c1)C(=NCc1n2c(C)nc1)c1ccccc1F
InChI InChI=1S/C18H13ClFN3/c1-11-21-9-13-10-22-18(14-4-2-3-5-16(14)20)15-8-12(19)6-7-17(15)23(11)13/h2-9H,10H2,1H3
Classification Click here for help
Compound class Synthetic organic
Ligand families/groups Benzodiazepine class drugs
Approved drug? Yes (FDA (2000), EMA (2011))
WHO Essential Medicine WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version.
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IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
4497 midazolam
Synonyms Click here for help
Buccolam® | Dormicum® | Nayzilam® | USL261 (nasal spray formulation) [1] | Versed®
Database Links Click here for help
Specialist databases
GPCRdb Ligand midazolam
Other databases
CAS Registry No. 59467-70-8 (source: Scifinder)
DrugBank Ligand DB00683
DrugCentral Ligand 1802
GtoPdb PubChem SID 178100372
PubChem CID 4192
RCSB PDB Ligand 08J
Search Google for chemical match using the InChIKey DDLIGBOFAVUZHB-UHFFFAOYSA-N
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UniChem Compound Search for chemical match using the InChIKey DDLIGBOFAVUZHB-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey DDLIGBOFAVUZHB-UHFFFAOYSA-N
Wikipedia Midazolam