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Compound class: Synthetic organic
Comment: A-971432 is an orally bioavailable selective sphingosine-1-phosphate receptor 5 (S1P5R) agonist, notably with no S1P1R activity. It is compound 29 in  and is claimed in patent WO2010093704 . A-971432 is suitable for differentiating S1P1 vs. S1P5 biology in vivo. The compound is being investigated for treatment efficacy in neurodegenerative disorders.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|Compound class||Synthetic organic|
|GtoPdb PubChem SID||329968436|
|Search Google for chemical match using the InChIKey||WAAWETUDFSIYSD-UHFFFAOYSA-N|
|Search Google for chemicals with the same backbone||WAAWETUDFSIYSD|
|UniChem Compound Search for chemical match using the InChIKey||WAAWETUDFSIYSD-UHFFFAOYSA-N|
|UniChem Connectivity Search for chemical match using the InChIKey||WAAWETUDFSIYSD-UHFFFAOYSA-N|
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Cat. No. 5766