ChEMBL ligand: CHEMBL1046 (177 JD, 177 J.D, 177 J.D., 177-JD, 6-aminocaproic acid, Amicar, Aminocaproic, Aminocaproic acid, CL 10304, CL-10304, CY-116, EACA, Epsikapron, Epsilcapramin, .epsilon.-aminocaproic acid, Epsilon-aminocaproic acid, Hexanoic acid, 6-amino-, NSC-26154, NSC-400230)
plasminogen/Plasminogen in Human [ChEMBL: CHEMBL1801] [GtoPdb: 2394] [UniProtKB: P00747] There should be some charts here, you may need to enable JavaScript!
Proton-coupled Amino acid Transporter 1/Proton-coupled amino acid transporter 1 in Human [ChEMBL: CHEMBL1914279] [GtoPdb: 1161] [UniProtKB: Q7Z2H8] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
plasminogen/Plasminogen in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1801] [GtoPdb: 2394] [UniProtKB: P00747]
ChEMBL	Binding affinity to human plasminogen K1 domain by ultrafiltration technique	B	5.05	pKd	9000	nM	Kd	J Med Chem (2020) 63: 1445-1472 [PMID:31658420]
ChEMBL	Binding affinity to full length Glu-plasminogen in human plasma assessed as inhibition of interaction with fibrin in presence of tPA	B	4.4	pIC50	40000	nM	IC50	ACS Med Chem Lett (2014) 5: 538-543 [PMID:24900876]
GtoPdb	Measuring inhibition of fibrinolysis in plasma.	-	4.4	pIC50	40000	nM	IC50	ACS Med Chem Lett (2014) 5: 538-543 [PMID:24900876]
Proton-coupled Amino acid Transporter 1/Proton-coupled amino acid transporter 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1914279] [GtoPdb: 1161] [UniProtKB: Q7Z2H8]
ChEMBL	Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting	B	1.54	pKi	-1.54	mM	pKi	Bioorg Med Chem (2011) 19: 6409-6418 [PMID:21955456]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]