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Synonyms: GR 144053 trihydrochloride | GR-144053 | GR144053
Compound class: Synthetic organic
Comment: GR 144053 inhibits paltelet aggregation by binding to integrin αIIb/β3 , thereby preventing integrin binding to fibrinogen. The compound is orally actrive and long-acting.
Note that we show the parent molecule here, but the trihydrochloride salt may be used experimentally.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|GR 144053 trihydrochloride | GR-144053 | GR144053
|CAS Registry No.
|GtoPdb PubChem SID
|RCSB PDB Ligand
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