compound 2q [PMID: 30986068] [Ligand Id: 10365] activity data from GtoPdb
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336] | ||||||||
| GtoPdb | In a biochemical HTRF assay measuring generation of PIP3 via phosphorylation of PIP2, using PI3Kα 14-602 fragment. | - | 6.57 | pIC50 | 270 | nM | IC50 | J Med Chem (2019) 62: 4370-4382 [PMID:30986068] |
| phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta in Human [GtoPdb: 2154] [UniProtKB: P42338] | ||||||||
| GtoPdb | In a biochemical HTRF assay measuring generation of PIP3 via phosphorylation of PIP2, using PI3Kβ 14-603 fragment. | - | 5.26 | pIC50 | 5460 | nM | IC50 | J Med Chem (2019) 62: 4370-4382 [PMID:30986068] |
| phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329] | ||||||||
| GtoPdb | In a biochemical HTRF assay measuring generation of PIP3 via phosphorylation of PIP2, using PI3Kδ 14-604 fragment. | - | 8.41 | pIC50 | 3.9 | nM | IC50 | J Med Chem (2019) 62: 4370-4382 [PMID:30986068] |
| phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736] | ||||||||
| GtoPdb | In a biochemical HTRF assay measuring generation of PIP3 via phosphorylation of PIP2, using PI3Kγ 14-558 fragment. | - | 5.42 | pIC50 | 3783 | nM | IC50 | J Med Chem (2019) 62: 4370-4382 [PMID:30986068] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
