busulfan [Ligand Id: 7136] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL820 (NCI-C01592, Busilvex, NSC-750, Myleran, Busulfex, Sulphabutin, Myelosan, Busulfan)
  • MMP9/Matrix metalloproteinase 9 in Human [ChEMBL: CHEMBL321] [GtoPdb: 1633] [UniProtKB: P14780]
  • This target only has 0 pki data point
  • 0
1 CHEMBL820_lig_chart_1 Matrix metalloproteinase 9 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
MMP9/Matrix metalloproteinase 9 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL321] [GtoPdb: 1633] [UniProtKB: P14780]
ChEMBL DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) B 5.28 pIC50 5215 nM IC50 DrugMatrix in vitro pharmacology data

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]