Ac-VEID-CHO [Ligand Id: 8566] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL478081
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Caspase 6/Caspase-6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3308] [GtoPdb: 1622] [UniProtKB: P55212]
ChEMBL Inhibition of human recombinant caspase 6 assessed as accumulation of fluorogenic product by fluorometric assay B 8.1 pIC50 8 nM IC50 J. Med. Chem. (2009) 52: 2188-2191 [PMID:19326941]
ChEMBL Inhibition of caspase 6 by fluorometric assay B 8.1 pIC50 8 nM IC50 Bioorg. Med. Chem. Lett. (2011) 21: 2192-2197 [PMID:21441025]
GtoPdb - - 8.1 pIC50 8 nM IC50 J Med Chem (2009) 52: 2188-91 [PMID:19326941]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]