IL-1β   Click here for help

GtoPdb Ligand ID: 4974

Synonyms: catabolin | interleukin-1 beta
Immunopharmacology Ligand
Comment: IL-1β is an IL-1 family cytokine produced from the IL1B gene. It is produced by activated macrophages as a proprotein which is cleaved by cytosolic caspase 1 to the mature, active molecule.
Species: Human
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Interleukins
Synonyms Click here for help
catabolin | interleukin-1 beta
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
IL1B interleukin 1 beta Human prepro-interleukin-1 beta IL-1B, IL1-BETA, IL1F2, interleukin 1, beta
Database Links Click here for help
DrugBank Target P01584 (Hs)
Ensembl Gene ENSG00000125538 (Hs)
GtoPdb PubChem SID 178101672
Human Protein Atlas ENSG00000125538 (Hs)
Immunopaedia Search IL-1β
UniProtKB P01584 (Hs)
Wikipedia Interleukin_1