glucagon-like peptide 2-(3-33)   Click here for help

GtoPdb Ligand ID: 3541

Abbreviated name: GLP-2 (3-33)
Comment: Mouse GLP-2(3-33) is different from human at residues 9 (Serine) and 17 (Threonine) and from rat at one residue in position 9 (Serine).

GLP-2(3-33) is the result of N-terminal dipeptide proteolytic cleavage of GLP-2(1-33) by serine protease dipeptidyl peptidase IV. GLP-2(3-33) is able to interact with GLP-2 receptors even though it remains unclear whether GLP-2(3-33) has a biological activity in vivo or may affect the biological activity of GLP-2(1-33) [1]
Species: Mouse
2D Structure
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SMILES / InChI / InChIKey
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Canonical SMILES NCCCCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)O)CC(=O)O)C(O)C)C(CC)C)NC(=O)C(C(O)C)NC(=O)C(NC(=O)C(C(CC)C)NC(=O)C(NC(=O)C(Cc1c[nH]c2c1cccc2)NC(=O)C(NC(=O)C(C(CC)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(C(O)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(C(CC)C)NC(=O)C(C(O)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC(=O)C(CC(=O)O)N)CO)Cc1ccccc1)CO)CC(=O)O)CCC(=O)O)CCSC)CO)CC(C)C)CC(=O)O)CC(=O)N)CC(C)C)C)CCCN=C(N)N)CC(=O)O)Cc1ccccc1)CC(=O)N)CC(C)C)CCC(=O)N
Isomeric SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H](N)CC(=O)O)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)CC
InChI InChI=1S/C156H243N39O54S/c1-21-73(11)118(147(240)173-90(44-46-108(159)203)132(225)193-123(79(17)200)152(245)171-88(42-33-34-49-157)131(224)188-121(76(14)24-4)150(243)195-124(80(18)201)153(246)185-104(155(248)249)64-117(217)218)189-142(235)95(54-72(9)10)175-136(229)98(57-84-65-165-87-41-32-31-40-85(84)87)178-138(231)100(60-110(161)205)184-148(241)119(74(12)22-2)190-143(236)97(56-83-38-29-26-30-39-83)176-140(233)102(62-115(213)214)180-128(221)89(43-35-50-164-156(162)163)172-151(244)122(78(16)199)192-126(219)77(15)167-133(226)93(52-70(5)6)174-137(230)99(59-109(160)204)179-141(234)103(63-116(215)216)181-134(227)94(53-71(7)8)183-149(242)120(75(13)23-3)191-154(247)125(81(19)202)194-146(239)107(69-198)186-130(223)92(48-51-250-20)170-129(222)91(45-47-112(207)208)169-139(232)101(61-114(211)212)182-145(238)106(68-197)187-135(228)96(55-82-36-27-25-28-37-82)177-144(237)105(67-196)168-111(206)66-166-127(220)86(158)58-113(209)210/h25-32,36-41,65,70-81,86,88-107,118-125,165,196-202H,21-24,33-35,42-64,66-69,157-158H2,1-20H3,(H2,159,203)(H2,160,204)(H2,161,205)(H,166,220)(H,167,226)(H,168,206)(H,169,232)(H,170,222)(H,171,245)(H,172,244)(H,173,240)(H,174,230)(H,175,229)(H,176,233)(H,177,237)(H,178,231)(H,179,234)(H,180,221)(H,181,227)(H,182,238)(H,183,242)(H,184,241)(H,185,246)(H,186,223)(H,187,228)(H,188,224)(H,189,235)(H,190,236)(H,191,247)(H,192,219)(H,193,225)(H,194,239)(H,195,243)(H,207,208)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H,217,218)(H,248,249)(H4,162,163,164)/t73-,74-,75-,76-,77-,78+,79+,80+,81+,86-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,118-,119-,120-,121-,122-,123-,124-,125-/m0/s1
InChI Key FGSZUMQGXARWAJ-XVADTHAUSA-N
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
Gcg glucagon Mouse preproglucagon GLP-1, Glu, glucagon-like peptide I
Database Links Click here for help
GtoPdb PubChem SID 135651776
Search Google for chemical match using the InChIKey FGSZUMQGXARWAJ-XVADTHAUSA-N
Search Google for chemicals with the same backbone FGSZUMQGXARWAJ
Search UniChem for chemical match using the InChIKey FGSZUMQGXARWAJ-XVADTHAUSA-N
Search UniChem for chemicals with the same backbone FGSZUMQGXARWAJ
UniProtKB P55095 (Mm)