Classification
Compound class	Synthetic organic

IUPAC Name

1-N'-[3-fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

International Nonproprietary Names
INN number	INN
10216	sitravatinib

Synonyms

GCD-516 | GCD516 | MGCD516

Comments

Sitravatinib (MGCD516) is an inhibitor of multiple receptor tyrosine kinases (RTKs) that was developed as an antineoplatic agent [1]. It targets several RTKs (e.g. c-Met, PDGFR, c-Kit and IGF1-R) whose overexpression has been shown to drive sarcoma cell growth

Database Links
CAS Registry No.	1123837-84-2 (source: WHO INN record)
GtoPdb PubChem SID	363894214
PubChem CID	25212148
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