olutasidenib [Ligand Id: 10319] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • isocitrate dehydrogenase (NADP(+)) 1 in Human [GtoPdb: 2884] [UniProtKB: O75874]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
isocitrate dehydrogenase (NADP(+)) 1 in Human [GtoPdb: 2884] [UniProtKB: O75874]
GtoPdb Inhibition of mutant IDH1 R132H and R132C in an enzymatic assay measuring inhibition of 2-HG production. - 7 pIC50 100 nM IC50 US9834539B2. Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors (2017)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.