olutasidenib [Ligand Id: 10319] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| isocitrate dehydrogenase (NADP(+)) 1 in Human [GtoPdb: 2884] [UniProtKB: O75874] | ||||||||
| GtoPdb | Inhibition of mutant IDH1 R132H and R132C in an enzymatic assay measuring inhibition of 2-HG production. | - | 7 | pIC50 | 100 | nM | IC50 | US9834539B2. Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors (2017) |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
