BIIB091 [Ligand Id: 11791] activity data from GtoPdb

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  • tyrosine kinase with immunoglobulin like and EGF like domains 1 in Human [GtoPdb: 1841] [UniProtKB: P35590]
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  • BMX non-receptor tyrosine kinase in Human [GtoPdb: 1942] [UniProtKB: P51813]
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  • Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
tyrosine kinase with immunoglobulin like and EGF like domains 1 in Human [GtoPdb: 1841] [UniProtKB: P35590]
GtoPdb - - 7.4 pKd 40 nM Kd J Med Chem (2022) 65: 1206-1224 [PMID:34734694]
BMX non-receptor tyrosine kinase in Human [GtoPdb: 1942] [UniProtKB: P51813]
GtoPdb - - 7.06 pKd 88 nM Kd J Med Chem (2022) 65: 1206-1224 [PMID:34734694]
Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
GtoPdb - - 10.15 pKd 0.07 nM Kd J Med Chem (2022) 65: 1206-1224 [PMID:34734694]
GtoPdb - - 9.3 pIC50 0.5 nM IC50 J Med Chem (2022) 65: 1206-1224 [PMID:34734694]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.