RIPK3 inhibitor 42 [Ligand Id: 10401] activity data from GtoPdb

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  • receptor interacting serine/threonine kinase 1 in Human [GtoPdb: 2189] [UniProtKB: Q13546]
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  • receptor interacting serine/threonine kinase 3 in Human [GtoPdb: 2191] [UniProtKB: Q9Y572]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
receptor interacting serine/threonine kinase 1 in Human [GtoPdb: 2189] [UniProtKB: Q13546]
GtoPdb - - 5.3 pKd >5000 nM Kd J Med Chem (2019) 62: 6665-6681 [PMID:31095385]
receptor interacting serine/threonine kinase 3 in Human [GtoPdb: 2191] [UniProtKB: Q9Y572]
GtoPdb - - 7.09 pKd 81 nM Kd J Med Chem (2019) 62: 6665-6681 [PMID:31095385]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.