fluorometholone   Click here for help

GtoPdb Ligand ID: 7079

Synonyms: Flarex® | FML®
Approved drug Immunopharmacology Ligand
fluorometholone is an approved drug (FDA (1972))
Compound class: Synthetic organic
Comment: Fluorometholone is a corticosteroid.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 74.6
Molecular weight 376.2
XLogP 1.95
No. Lipinski's rules broken 0
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Canonical SMILES O=C1C=CC2(C(=C1)C(C)CC1C2(F)C(O)CC2(C1CCC2(O)C(=O)C)C)C
Isomeric SMILES O=C1C=C[C@]2(C(=C1)[C@@H](C)C[C@@H]1[C@]2(F)[C@@H](O)C[C@]2([C@H]1CC[C@]2(O)C(=O)C)C)C
InChI InChI=1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1972))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
803 fluorometholone
Synonyms Click here for help
Flarex® | FML®
Database Links Click here for help
CAS Registry No. 426-13-1
ChEMBL Ligand CHEMBL1200600
DrugBank Ligand DB00324
DrugCentral Ligand 1208
GtoPdb PubChem SID 178103658
PubChem CID 9878
Search Google for chemical match using the InChIKey FAOZLTXFLGPHNG-KNAQIMQKSA-N
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Search PubMed clinical trials fluorometholone
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UniChem Compound Search for chemical match using the InChIKey FAOZLTXFLGPHNG-KNAQIMQKSA-N
UniChem Connectivity Search for chemical match using the InChIKey FAOZLTXFLGPHNG-KNAQIMQKSA-N
Wikipedia Fluorometholone