Synonyms: compound 38 [PMID: 38949959] | YX-862
Compound class:
Synthetic organic
Comment: YX862 ia a PROTAC degrader of histone deacetylase 8 (HDAC8) [1]. It is a von Hippel-Lindau (VHL)-recruiting PROTAC with a hydrazide warhead to engage the target and it was designed as a potential antitumour agent.
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Classification ![]() |
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Compound class | Synthetic organic |
Ligand families/groups | PROTACs, molecular glues and other degraders |
Synonyms ![]() |
compound 38 [PMID: 38949959] | YX-862 |
Database Links ![]() |
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GtoPdb PubChem SID | 500839893 |
PubChem CID | 172011804 |
Search Google for chemical match using the InChIKey | ZOSWUNAJRAEGEW-YTIGDUPRSA-N |
Search Google for chemicals with the same backbone | ZOSWUNAJRAEGEW |
UniChem Compound Search for chemical match using the InChIKey | ZOSWUNAJRAEGEW-YTIGDUPRSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | ZOSWUNAJRAEGEW-YTIGDUPRSA-N |