hINSL5: A8-21 (T9R)   Click here for help

GtoPdb Ligand ID: 9324

Comment: This is insulin-like peptide 5 (INSL5) analogue 7 with single-point substitution T9R [1]. It is the minimal sequence required to retain INSL5 mimetic activity. Like ghrelin, INSL5 is an orexigenic gut hormone that plays a physiological role in driving food intake. INSL5 acts via the relaxin family peptide receptor 4 (RXFP4). INSL5 mimetics are being investigated for their potential to provide clinical benefit in the treatment of anorexia.
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Classification Click here for help
Compound class Peptide or derivative
Database Links Click here for help
GtoPdb PubChem SID 318164843