[Ala11,22,28]VIP [Ligand Id: 2278] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| PAC1 receptor in Human [GtoPdb: 370] [UniProtKB: P41586] | ||||||||
| GtoPdb | calcium influx in CHO cells stably expressing recombinant receptor | - | 5 | pEC50 | >10000 | nM | EC50 | Neuropharmacology (2006) 51: 1086-98 [PMID:16930633] |
| GtoPdb | cyclic AMP formation in CHO cells stably expressing recombinant receptor | - | 5.8 | pEC50 | 1582 | nM | EC50 | Neuropharmacology (2006) 51: 1086-98 [PMID:16930633] |
| VPAC1 receptor in Human [GtoPdb: 371] [UniProtKB: P32241] | ||||||||
| GtoPdb | inhibition of [125I]-VIP binding to membranes from CHO cells stably expressing the recombinant receptor | - | 8.1 | pKi | 7.4 | nM | Ki | J Biol Chem (2000) 275: 24003-12 [PMID:10801840] |
| GtoPdb | calcium influx in CHO cells stably expressing recombinant receptor | - | 7.6 | pEC50 | 25.6 | nM | EC50 | Neuropharmacology (2006) 51: 1086-98 [PMID:16930633] |
| GtoPdb | stimulation of cyclic AMP formation in CHO cells stably expressing the recombinant receptor | - | 9.4 | pEC50 | 0.4 | nM | EC50 | J Biol Chem (2000) 275: 24003-12 [PMID:10801840] |
| GtoPdb | cyclic AMP formation in CHO cells stably expressing recombinant receptor | - | 10.2 | pEC50 | 0.06 | nM | EC50 | Neuropharmacology (2006) 51: 1086-98 [PMID:16930633] |
| VPAC2 receptor in Human [GtoPdb: 372] [UniProtKB: P41587] | ||||||||
| GtoPdb | inhibition of [125I]-VIP binding to membranes from CHO cells stably expressing the recombinant receptor | - | 5.6 | pKi | 2352 | nM | Ki | J Biol Chem (2000) 275: 24003-12 [PMID:10801840] |
| GtoPdb | calcium influx in CHO cells stably expressing recombinant receptor | - | 5 | pEC50 | >10000 | nM | EC50 | Neuropharmacology (2006) 51: 1086-98 [PMID:16930633] |
| GtoPdb | cyclic AMP formation in CHO cells stably expressing recombinant receptor | - | 5 | pEC50 | >10000 | nM | EC50 | Neuropharmacology (2006) 51: 1086-98 [PMID:16930633] |
| GtoPdb | stimulation of cyclic AMP formation in CHO cells stably expressing the recombinant receptor | - | 5.9 | pEC50 | 1222 | nM | EC50 | J Biol Chem (2000) 275: 24003-12 [PMID:10801840] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
