Synonyms: BCH-189 | BCH189 | Epivir® | GR-109714X
lamivudine is an approved drug (FDA (1995), EMA (1996))
Compound class:
Synthetic organic
Comment: Lamivudine is an antiretroviral drug. It inhibits HIV-1 reverse transcriptase, and it belongs to the nucleoside reverse transcriptase inhibitors (NRTI) class of antiretriviral drugs.
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Classification | |
Compound class | Synthetic organic |
Approved drug? | Yes (FDA (1995), EMA (1996)) |
WHO Essential Medicine | WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version. Click to view more information about the WHO Model Lists of Essential Medicines. |
IUPAC Name |
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one |
International Nonproprietary Names | |
INN number | INN |
6908 | lamivudine |
Synonyms |
BCH-189 | BCH189 | Epivir® | GR-109714X |
Database Links | |
BindingDB Ligand | 50366817 |
ChEBI | CHEBI:63577 |
ChEMBL Ligand | CHEMBL141 |
DrugBank Ligand | DB00709 |
GtoPdb PubChem SID | 483123221 |
PubChem CID | 60825 |
RCSB PDB Ligand | 3TC |
Search Google for chemical match using the InChIKey | JTEGQNOMFQHVDC-NKWVEPMBSA-N |
Search Google for chemicals with the same backbone | JTEGQNOMFQHVDC |
Search PubMed clinical trials | lamivudine |
Search PubMed titles | lamivudine |
Search PubMed titles/abstracts | lamivudine |
UniChem Compound Search for chemical match using the InChIKey | JTEGQNOMFQHVDC-NKWVEPMBSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | JTEGQNOMFQHVDC-NKWVEPMBSA-N |