Synonyms: ABBV/GLPG-3221 | compound 19 [PMID: 31749908]
Compound class:
Synthetic organic
Comment: ABBV-3221(GLPG-3221) is a novel cystic fibrosis transmembrane conductance regulator (CFTR) corrector that is being developed in a collaboration between AbbVie and Galapagos for the treatment of cystic fibrosis [1]. It was designed to provide improved clinical efficacy when used in a triple combination with a CFTR potentiator and a second, but mechanistically distinct, corrector molecule.
|
|
Classification ![]() |
|
Compound class | Synthetic organic |
IUPAC Name ![]() |
(2S,3R,4S,5S)-3-tert-Butyl-4-{[2-methoxy-5-(trifluoromethyl)pyridin-3-yl]methoxy}-5-(2-methylphenyl)-1-[(2S)-oxane-2-carbonyl]pyrrolidine-2-carboxylic acid |
Synonyms ![]() |
ABBV/GLPG-3221 | compound 19 [PMID: 31749908] |
Database Links ![]() |
|
GtoPdb PubChem SID | 404859024 |
PubChem CID | 139443340 |
Search Google for chemical match using the InChIKey | YFEYDNAKCSOOOG-YCXOGWGTSA-N |
Search Google for chemicals with the same backbone | YFEYDNAKCSOOOG |
UniChem Compound Search for chemical match using the InChIKey | YFEYDNAKCSOOOG-YCXOGWGTSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | YFEYDNAKCSOOOG-YCXOGWGTSA-N |