bazedoxifene   Click here for help

GtoPdb Ligand ID: 7355

Synonyms: Conbriza® | TSE-424 | Viviant® | WAY-140424
Approved drug PDB Ligand
bazedoxifene is an approved drug (EMA (2009), FDA (2013))
Compound class: Synthetic organic
Comment: Bazedoxifene is a selective estrogen receptor modulator (SERM).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 57.86
Molecular weight 470.26
XLogP 6.5
No. Lipinski's rules broken 1
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Canonical SMILES Oc1ccc2c(c1)c(C)c(n2Cc1ccc(cc1)OCCN1CCCCCC1)c1ccc(cc1)O
Isomeric SMILES Oc1ccc2c(c1)c(C)c(n2Cc1ccc(cc1)OCCN1CCCCCC1)c1ccc(cc1)O
InChI InChI=1S/C30H34N2O3/c1-22-28-20-26(34)12-15-29(28)32(30(22)24-8-10-25(33)11-9-24)21-23-6-13-27(14-7-23)35-19-18-31-16-4-2-3-5-17-31/h6-15,20,33-34H,2-5,16-19,21H2,1H3
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (EMA (2009), FDA (2013))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
8168 bazedoxifene
Synonyms Click here for help
Conbriza® | TSE-424 | Viviant® | WAY-140424
Database Links Click here for help
CAS Registry No. 198481-32-2
ChEMBL Ligand CHEMBL46740
DrugCentral Ligand 4334
GtoPdb PubChem SID 178103927
PubChem CID 154257
RCSB PDB Ligand 29S
Search Google for chemical match using the InChIKey UCJGJABZCDBEDK-UHFFFAOYSA-N
Search Google for chemicals with the same backbone UCJGJABZCDBEDK
Search PubMed clinical trials bazedoxifene
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SynPHARM 79264 (in complex with Estrogen receptor-α)
UniChem Compound Search for chemical match using the InChIKey UCJGJABZCDBEDK-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey UCJGJABZCDBEDK-UHFFFAOYSA-N
Wikipedia Bazedoxifene