compound 4d [PMID: 25489658] [Ligand Id: 8483] activity data from GtoPdb

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  • kallikrein related peptidase 5 in Human [GtoPdb: 2375] [UniProtKB: Q9Y337]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 kallikrein related peptidase 5 Human
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  • kallikrein related peptidase 7 in Human [GtoPdb: 2377] [UniProtKB: P49862]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 kallikrein related peptidase 7 Human
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  • ST14 transmembrane serine protease matriptase in Human [GtoPdb: 2418] [UniProtKB: Q9Y5Y6]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 ST14 transmembrane serine protease matriptase Human
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  • kallikrein related peptidase 14 in Human [GtoPdb: 2866] [UniProtKB: Q9P0G3]
  • This target only has 0 pki data point
  • 0
4 _lig_chart_4 kallikrein related peptidase 14 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
kallikrein related peptidase 5 in Human [GtoPdb: 2375] [UniProtKB: Q9Y337]
GtoPdb - - 6.04 pIC50 920 nM IC50 J Med Chem (2015) 58: 598-612 [PMID:25489658]
kallikrein related peptidase 7 in Human [GtoPdb: 2377] [UniProtKB: P49862]
GtoPdb - - 7.19 pIC50 64 nM IC50 J Med Chem (2015) 58: 598-612 [PMID:25489658]
ST14 transmembrane serine protease matriptase in Human [GtoPdb: 2418] [UniProtKB: Q9Y5Y6]
GtoPdb - - 5.85 pIC50 1420 nM IC50 J Med Chem (2015) 58: 598-612 [PMID:25489658]
kallikrein related peptidase 14 in Human [GtoPdb: 2866] [UniProtKB: Q9P0G3]
GtoPdb - - 5.54 pIC50 2900 nM IC50 J Med Chem (2015) 58: 598-612 [PMID:25489658]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.