compound 4d [PMID: 25489658] [Ligand Id: 8483] activity data from GtoPdb

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  • kallikrein related peptidase 5 in Human [GtoPdb: 2375] [UniProtKB: Q9Y337]
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  • kallikrein related peptidase 7 in Human [GtoPdb: 2377] [UniProtKB: P49862]
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  • ST14 transmembrane serine protease matriptase in Human [GtoPdb: 2418] [UniProtKB: Q9Y5Y6]
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  • kallikrein related peptidase 14 in Human [GtoPdb: 2866] [UniProtKB: Q9P0G3]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
kallikrein related peptidase 5 in Human [GtoPdb: 2375] [UniProtKB: Q9Y337]
GtoPdb - - 6.04 pIC50 920 nM IC50 J Med Chem (2015) 58: 598-612 [PMID:25489658]
kallikrein related peptidase 7 in Human [GtoPdb: 2377] [UniProtKB: P49862]
GtoPdb - - 7.19 pIC50 64 nM IC50 J Med Chem (2015) 58: 598-612 [PMID:25489658]
ST14 transmembrane serine protease matriptase in Human [GtoPdb: 2418] [UniProtKB: Q9Y5Y6]
GtoPdb - - 5.85 pIC50 1420 nM IC50 J Med Chem (2015) 58: 598-612 [PMID:25489658]
kallikrein related peptidase 14 in Human [GtoPdb: 2866] [UniProtKB: Q9P0G3]
GtoPdb - - 5.54 pIC50 2900 nM IC50 J Med Chem (2015) 58: 598-612 [PMID:25489658]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.