bofutrelvir [Ligand Id: 11070] activity data from GtoPdb

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  • CoV 3C-like (main) protease in SARS-CoV-2 [GtoPdb: 3111]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CoV 3C-like (main) protease in SARS-CoV-2 [GtoPdb: 3111]
GtoPdb In vitro inhibition of recombinant SARS-CoV-2 Mpro enzymatic activity. - 7.28 pIC50 53 nM IC50 Science (2020) 368: 1331-1335 [PMID:32321856]
GtoPdb - - 7.85 pIC50 14 nM IC50 Bioorg Med Chem Lett (2021) 48: 128263 [PMID:34271072]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.