eprosartan   Click here for help

GtoPdb Ligand ID: 588

Synonyms: Eprozar® | SK-108566 | Teveten®
Approved drug
eprosartan is an approved drug (FDA (1997))
Compound class: Synthetic organic
Comment: Eprosartan is an antagonist of the type 1 angiotensin II receptor (AGTR1).
Marketed formulations may contain eprosartan mesylate (PubChem CID 5282474).
Click here for help
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: eprosartan

2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 120.66
Molecular weight 424.15
XLogP 3.89
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Click here for help
Canonical SMILES CCCCc1ncc(n1Cc1ccc(cc1)C(=O)O)C=C(C(=O)O)Cc1cccs1
Isomeric SMILES CCCCc1ncc(n1Cc1ccc(cc1)C(=O)O)/C=C(/C(=O)O)\Cc1cccs1
InChI InChI=1S/C23H24N2O4S/c1-2-3-6-21-24-14-19(12-18(23(28)29)13-20-5-4-11-30-20)25(21)15-16-7-9-17(10-8-16)22(26)27/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H,26,27)(H,28,29)/b18-12+
InChI Key OROAFUQRIXKEMV-LDADJPATSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1997))
IUPAC Name Click here for help
4-[[2-butyl-5-[(E)-3-hydroxy-3-oxo-2-(thiophen-2-ylmethyl)prop-1-enyl]imidazol-1-yl]methyl]benzoic acid
International Nonproprietary Names Click here for help
INN number INN
7223 eprosartan
Synonyms Click here for help
Eprozar® | SK-108566 | Teveten®
Database Links Click here for help
CAS Registry No. 133040-01-4 (source: Scifinder)
ChEBI CHEBI:4814
ChEMBL Ligand CHEMBL813
DrugBank Ligand DB00876
DrugCentral Ligand 1037
GtoPdb PubChem SID 135650236
PubChem CID 5281037
Search Google for chemical match using the InChIKey OROAFUQRIXKEMV-LDADJPATSA-N
Search Google for chemicals with the same backbone OROAFUQRIXKEMV
Search PubMed clinical trials eprosartan
Search PubMed titles eprosartan
Search PubMed titles/abstracts eprosartan
Search UniChem for chemical match using the InChIKey OROAFUQRIXKEMV-LDADJPATSA-N
Search UniChem for chemicals with the same backbone OROAFUQRIXKEMV
Wikipedia Eprosartan