LY2886721 [Ligand Id: 6475] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL2396989
  • beta-secretase 1 in Human [GtoPdb: 2330] [UniProtKB: P56817]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
beta-secretase 1 in Human [GtoPdb: 2330] [UniProtKB: P56817]
GtoPdb - - 7.7 pIC50 20.3 nM IC50 Alzheimers Dement (2012) 8: 95

ChEMBL data shown on this page come from version 26:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]