Synonyms: compound 54 [WO2018071348]
Compound class:
Synthetic organic
Comment: The chemical structure for enrupatinib was obtained from WHO proposed INN list 131 (August 2024), in which it is described as a colony-stimulating factor 1 receptor (CSF1R) inhibitor and antineoplastic. The structure matches to one of the compounds claimed in patent WO2018071348A1 (assigned to Taiwan's Development Center for Biotechnology, or DCB) [1]. The DCB does not list a research code for this compound on the disclosed pipeline webpage.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Classification | |
Compound class | Synthetic organic |
IUPAC Name |
6-[3-methoxy-4-[(6-methylpyridin-3-yl)methoxy]anilino]-3-morpholin-4-ylquinoxaline-5-carbonitrile |
International Nonproprietary Names | |
INN number | INN |
13274 | enrupatinib |
Synonyms |
compound 54 [WO2018071348] |
Database Links | |
BindingDB Ligand | 447547 |
CAS Registry No. | 2222689-47-4 (source: WHO INN record) |
GtoPdb PubChem SID | 500839899 |
PubChem CID | 134442338 |
Search Google for chemical match using the InChIKey | UGKFKFGVNJJPOL-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | UGKFKFGVNJJPOL |
Search PubMed clinical trials | enrupatinib |
Search PubMed titles | enrupatinib |
Search PubMed titles/abstracts | enrupatinib |
UniChem Compound Search for chemical match using the InChIKey | UGKFKFGVNJJPOL-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | UGKFKFGVNJJPOL-UHFFFAOYSA-N |