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Synonyms: Entocort® | Eohilia® (budesonide oral suspension) | Jorveza® | Pulmicort® | S-1320 | Uceris®
budesonide is an approved drug (FDA (1997), EMA (2018))
Compound class: Synthetic organic
Comment: Budesonide is a glucocorticoid steroid. The INN document specifies that the approved drug consists of a racemic mixture of two epimers, based on the stereocentre of the carbon where the butyl chain meets the rest of the molecule. Our structure does not specify strereochemistry at this point and represents the mixture. The two epimers are represented by CID 40000 and CID 63006.
COVID-19: Results from a Phase 2 clinical trial have shown that a short duration administration of budesonide in the early phase of SARS-CoV-2 infection reduces both the likelihood of needing urgent medical care and time to recovery .
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
View more information in the IUPHAR Pharmacology Education Project: budesonide
|Compound class||Synthetic organic|
|Approved drug?||Yes (FDA (1997), EMA (2018))|
|WHO Essential Medicine||WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version.
Click to view more information about the WHO Model Lists of Essential Medicines.
|International Nonproprietary Names|
|Entocort® | Eohilia® (budesonide oral suspension) | Jorveza® | Pulmicort® | S-1320 | Uceris®|
|CAS Registry No.||51333-22-3|
|GtoPdb PubChem SID||178104006|
|Search Google for chemical match using the InChIKey||VOVIALXJUBGFJZ-KWVAZRHASA-N|
|Search Google for chemicals with the same backbone||VOVIALXJUBGFJZ|
|Search PubMed clinical trials||budesonide|
|Search PubMed titles||budesonide|
|Search PubMed titles/abstracts||budesonide|
|SynPHARM||84619 (in complex with Glucocorticoid receptor)|
|UniChem Compound Search for chemical match using the InChIKey||VOVIALXJUBGFJZ-KWVAZRHASA-N|
|UniChem Connectivity Search for chemical match using the InChIKey||VOVIALXJUBGFJZ-KWVAZRHASA-N|
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Budesonide (links to external site)
Cat. No. 2671