ZK159222 [Ligand Id: 2789] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL2112314 (ZK-159222) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Vitamin D receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1977] [GtoPdb: 605] [UniProtKB: P11473] | ||||||||
| GtoPdb | - | - | 7.5 | pIC50 | 29 | nM | IC50 |
Bioorg Med Chem (2003) 11: 3621-31 [PMID:12901907]; Chem Biol (2000) 7: 885-94 [PMID:11094341] |
| ChEMBL | Effective concentration required for inhibition of Vitamin D3 receptor | B | 9.4 | pEC50 | 0.4 | nM | EC50 | J Med Chem (2004) 47: 1956-1961 [PMID:15055995] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
