glipizide   Click here for help

GtoPdb Ligand ID: 6821

Synonyms: CP-28720 | Glucotrol® | K-4024
Approved drug
glipizide is an approved drug (FDA (1984))
Compound class: Synthetic organic
Comment: A sulfonylurea family drug inhibiting sulfonylurea receptor 1 (ABCC8)/Kir6.2 (KCNJ11).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 138.53
Molecular weight 445.18
XLogP 2.26
No. Lipinski's rules broken 0
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Canonical SMILES Cc1ncc(nc1)C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1
Isomeric SMILES Cc1ncc(nc1)C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1
InChI InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1984))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
3090 glipizide
Synonyms Click here for help
CP-28720 | Glucotrol® | K-4024
Database Links Click here for help
CAS Registry No. 29094-61-9
ChEMBL Ligand CHEMBL1073
DrugBank Ligand DB01067
DrugCentral Ligand 1301
GtoPdb PubChem SID 178103427
PubChem CID 3478
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UniChem Compound Search for chemical match using the InChIKey ZJJXGWJIGJFDTL-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey ZJJXGWJIGJFDTL-UHFFFAOYSA-N
Wikipedia Glipizide