pemirolast [Ligand Id: 7329] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1201198 (Pemirolast, Pemirox, Permirolast)
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GPR35/G protein-coupled receptor GPR35 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2390812] [GtoPdb: 102] [UniProtKB: Q33BM1]
ChEMBL Agonist activity at recombinant rat N-terminal FLAG/eYFP-fused GPR35 expressed in HEK293 cells assessed as induction of beta-arrestin recruitment by BRET assay F 7.02 pEC50 95 nM EC50 ACS Med Chem Lett (2018) 9: 422-427 [PMID:29795753]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]