cyclizine

Ligand id: 7151

Name: cyclizine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 6.48
Molecular weight 266.18
XLogP 2.99
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (date unknown))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
1-(diphenylmethyl)-4-methylpiperazine
International Nonproprietary Names
INN number INN
176 cyclizine
Synonyms
Marezine®
Comments
Cyclizine is an antihistamine drug used primarily for its anti-nausea and antiemetic actions.
Cyclizine is on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).
Database Links
CAS Registry No. 82-92-8
ChEMBL Ligand CHEMBL648
DrugBank Ligand DB01176
GtoPdb PubChem SID 178103726
PubChem CID 6726
Search Google for chemical match using the InChIKey UVKZSORBKUEBAZ-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey UVKZSORBKUEBAZ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone UVKZSORBKUEBAZ
Wikipedia Cyclizine