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tesidolumab   Click here for help

GtoPdb Ligand ID: 8711

Synonyms: LFG-316 | LFG316
Compound class: Antibody
Comment: Tesidolumab is a fully human monoclonal antibody targeting complement C5. Like eculizumab, this investigational monoclonal inhibits terminal complement activation.
Peptide sequence and secondary structural information for this antibody are available from its IMGT/mAb-DB record.
Peptide sequence alignment analysis using the heavy and light variable domains of tesidolumab provide 100% matches to SEQ ID NOs 7 and 8 respectively from patent US8241628 [1]. These peptide sequences correspond to antibody (MOR0)8109 in said patent.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
10051 tesidolumab
Synonyms Click here for help
LFG-316 | LFG316
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 535
Other databases
GtoPdb PubChem SID 252827369
Search PubMed clinical trials tesidolumab
Search PubMed titles tesidolumab
Search PubMed titles/abstracts tesidolumab