AZD1656   Click here for help

GtoPdb Ligand ID: 7701

Synonyms: AZD 1656 | AZD-1656
Compound class: Synthetic organic
Comment: AZD1656 activates glucokinase (GCK; P35557). AZD1656 was developed as a potential treatment for diabetes. This compound is included in AstaZeneca's Open Innovation Pharmacology Toolbox.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 128.66
Molecular weight 478.2
XLogP 1.21
No. Lipinski's rules broken 0
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Canonical SMILES COCC(Oc1cc(Oc2ncc(nc2)C(=O)N2CCC2)cc(c1)C(=O)Nc1ncc(nc1)C)C
Isomeric SMILES COC[C@@H](Oc1cc(Oc2ncc(nc2)C(=O)N2CCC2)cc(c1)C(=O)Nc1ncc(nc1)C)C
InChI InChI=1S/C24H26N6O5/c1-15-10-27-21(12-25-15)29-23(31)17-7-18(34-16(2)14-33-3)9-19(8-17)35-22-13-26-20(11-28-22)24(32)30-5-4-6-30/h7-13,16H,4-6,14H2,1-3H3,(H,27,29,31)/t16-/m0/s1
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
Synonyms Click here for help
AZD 1656 | AZD-1656
Database Links Click here for help
ChEMBL Ligand CHEMBL3219124
GtoPdb PubChem SID 223366034
PubChem CID 16039797
Search Google for chemical match using the InChIKey FJEJHJINOKKDCW-INIZCTEOSA-N
Search Google for chemicals with the same backbone FJEJHJINOKKDCW
UniChem Compound Search for chemical match using the InChIKey FJEJHJINOKKDCW-INIZCTEOSA-N
UniChem Connectivity Search for chemical match using the InChIKey FJEJHJINOKKDCW-INIZCTEOSA-N