CX516 [Ligand Id: 4165] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL136800 (BDP 12, CX-516, Cx516, BDP-12, CX 516)
  • GluA3/GluA4/Glutamate receptor AMPA 3/4 in Rat [ChEMBL: CHEMBL3885582] [GtoPdb: 446, 447] [UniProtKB: P19492, P19493]
  • This target only has 0 pki data point
1 CHEMBL136800_lig_chart_1 Glutamate receptor AMPA 3/4 Rat
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GluA3/GluA4/Glutamate receptor AMPA 3/4 in Rat (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL3885582] [GtoPdb: 446, 447] [UniProtKB: P19492, P19493]
ChEMBL Inhibition of GluR3/4 rat in hippocampal neuron B 4.02 pEC50 95000 nM EC50 J. Med. Chem. (2010) 53: 7271-7279 [PMID:20839777]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]