CX516 [Ligand Id: 4165] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL136800 (Ampalex, BDP 12, BDP-12, Cx516, CX 516, CX-516)
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GluA3/GluA4/Glutamate receptor AMPA 3/4 in Rat (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL3885582] [GtoPdb: 446447] [UniProtKB: P19492P19493]
ChEMBL Inhibition of GluR3/4 rat in hippocampal neuron B 4.02 pEC50 95000 nM EC50 J Med Chem (2010) 53: 7271-7279 [PMID:20839777]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]