TIPPψ [Ligand Id: 1637] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL3038183
  • δ receptor in Human [GtoPdb: 317] [UniProtKB: P41143]
  • δ receptor/Delta opioid receptor in Rat [ChEMBL: CHEMBL269] [GtoPdb: 317] [UniProtKB: P33533]
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  • μ receptor/Mu opioid receptor in Rat [ChEMBL: CHEMBL270] [GtoPdb: 319] [UniProtKB: P33535]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
δ receptor in Human [GtoPdb: 317] [UniProtKB: P41143]
GtoPdb - - 9 pKi - - - NIDA Res Monogr (1998) 178: 440-66 [PMID:9686407];
J Med Chem (1993) 36: 3182-7 [PMID:8230106]
δ receptor/Delta opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL269] [GtoPdb: 317] [UniProtKB: P33533]
ChEMBL Displacement of [3H]DSLET from delta opioid receptor in rat brain membranes B 9.51 pKi 0.31 nM Ki Bioorg. Med. Chem. Lett. (2013) 23: 5082-5085 [PMID:23932788]
Kappa opioid receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3952] [UniProtKB: P41144]
ChEMBL Displacement of [3H]U69,593 from kappa opioid receptor in guinea pig brain membranes B 6 pKi >1000 nM Ki Bioorg. Med. Chem. Lett. (2013) 23: 5082-5085 [PMID:23932788]
μ receptor/Mu opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL270] [GtoPdb: 319] [UniProtKB: P33535]
ChEMBL Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes B 5.49 pKi 3230 nM Ki Bioorg. Med. Chem. Lett. (2013) 23: 5082-5085 [PMID:23932788]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]