Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
ChEMBL ligand: CHEMBL449395 (SDZ-64-412) |
---|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
PAF receptor/Platelet activating factor receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL250] [GtoPdb: 334] [UniProtKB: P25105] | ||||||||
GtoPdb | - | - | 7.2 | pIC50 | - | - | - | J Pharmacol Exp Ther (1988) 247: 617-23 [PMID:3183958] |
ChEMBL | In vitro PAF antagonistic activity by determining [3H]PAF binding to the PAF-receptor of human platelets | B | 7.22 | pIC50 | 60 | nM | IC50 | J Med Chem (1993) 36: 3098-3102 [PMID:8230095] |
ChEMBL | In vitro inhibition of [3H]PAF receptor binding to washed human platelet membranes | B | 7.4 | pIC50 | 40 | nM | IC50 | Bioorg Med Chem Lett (1993) 3: 1493-1498 |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]