L-363,377 [Ligand Id: 2048] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL2052017 (L-363377) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| SST2 receptor/Somatostatin receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1804] [GtoPdb: 356] [UniProtKB: P30874] | ||||||||
| GtoPdb | - | - | 9.3 | pKi | - | - | - |
Science (1998) 282: 737-40 [PMID:9784130]; Proc Natl Acad Sci USA (1998) 95: 10836-41 [PMID:9724791] |
| ChEMBL | Binding affinity towards human sst2 receptor expressed in CHO-K1 cells | B | 9.3 | pKi | 0.5 | nM | Ki | J Med Chem (1998) 41: 2175-2179 [PMID:9632348] |
| SST2 receptor in Mouse [GtoPdb: 356] [UniProtKB: P30875] | ||||||||
| GtoPdb | - | - | 9.4 | pIC50 | - | - | - | Metab Clin Exp (1996) 45: 12-3 [PMID:8769370] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
