tarlatamab   Click here for help

GtoPdb Ligand ID: 12969

Synonyms: AMG 757 | AMG-757 | AMG757
Compound class: Antibody
Comment: Tarlatamab (AMG 757) is a bispecific T cell engager (BiTE®) type anti-Delta-like ligand 3 (DLL3) monoclonal antibody [4-5]. It co-engages DLL3 on cancer cells and CD3E on T cells to promote T cell-mediated tumor lysis. The rationale for investigating DLL3 as a cancer drug target is reviewed in [3].
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Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
11420 tarlatamab
Synonyms Click here for help
AMG 757 | AMG-757 | AMG757
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 1073
Other databases
GtoPdb PubChem SID 485206090
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