alizapride   Click here for help

GtoPdb Ligand ID: 11141

Synonyms: Limican® | Litican® | Nausilex® | Plitican® | Superan® | Vergentan®
Approved drug
alizapride is an approved drug
Compound class: Synthetic organic
Comment: Dopamine D2 receptor antagonist with prokinetic and antiemetic effects which can also be used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.
Click here for help
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 83.14
Molecular weight 315.17
XLogP 1.53
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Click here for help
Canonical SMILES C=CCN1CCCC1CNC(=O)c1cc2[nH]nnc2cc1OC
Isomeric SMILES C=CCN1CCCC1CNC(=O)c1cc2[nH]nnc2cc1OC
InChI InChI=1S/C16H21N5O2/c1-3-6-21-7-4-5-11(21)10-17-16(22)12-8-13-14(19-20-18-13)9-15(12)23-2/h3,8-9,11H,1,4-7,10H2,2H3,(H,17,22)(H,18,19,20)
InChI Key KSEYRUGYKHXGFW-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name Click here for help
6-methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-carboxamide
International Nonproprietary Names Click here for help
INN number INN
4823 alizapride
Synonyms Click here for help
Limican® | Litican® | Nausilex® | Plitican® | Superan® | Vergentan®
Database Links Click here for help
CAS Registry No. 59338-93-1
ChEMBL Ligand CHEMBL290194
DrugCentral Ligand 120
GtoPdb PubChem SID 434122201
PubChem CID 135413504
Search Google for chemical match using the InChIKey KSEYRUGYKHXGFW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone KSEYRUGYKHXGFW
Search PubMed clinical trials alizapride
Search PubMed titles alizapride
Search PubMed titles/abstracts alizapride
Search UniChem for chemical match using the InChIKey KSEYRUGYKHXGFW-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone KSEYRUGYKHXGFW