alizapride   Click here for help

GtoPdb Ligand ID: 11141

Synonyms: Limican® | Litican® | Nausilex® | Plitican® | Superan® | Vergentan®
Approved drug
alizapride is an approved drug
Compound class: Synthetic organic
Comment: Dopamine D2 receptor antagonist with prokinetic and antiemetic effects which can also be used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. The WHO INN record for alizapride provides the CAS registry number 59338-93-1. This CAS number maps to PubChem CID 135413504 (vergentan), which is a tautomer of alizapride.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 83.14
Molecular weight 315.17
XLogP 1.53
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES C=CCN1CCCC1CNC(=O)c1cc2[nH]nnc2cc1OC
Isomeric SMILES C=CCN1CCCC1CNC(=O)c1cc2[nH]nnc2cc1OC
InChI InChI=1S/C16H21N5O2/c1-3-6-21-7-4-5-11(21)10-17-16(22)12-8-13-14(19-20-18-13)9-15(12)23-2/h3,8-9,11H,1,4-7,10H2,2H3,(H,17,22)(H,18,19,20)
InChI Key KSEYRUGYKHXGFW-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name Click here for help
6-methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-carboxamide
International Nonproprietary Names Click here for help
INN number INN
4823 alizapride
Synonyms Click here for help
Limican® | Litican® | Nausilex® | Plitican® | Superan® | Vergentan®
Database Links Click here for help
Specialist databases
GPCRdb Ligand alizapride
Other databases
CAS Registry No. 59338-93-1
DrugCentral Ligand 120
GtoPdb PubChem SID 434122201
PubChem CID 43008
Search Google for chemical match using the InChIKey KSEYRUGYKHXGFW-UHFFFAOYSA-N
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UniChem Compound Search for chemical match using the InChIKey KSEYRUGYKHXGFW-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey KSEYRUGYKHXGFW-UHFFFAOYSA-N