ChEMBL ligand: CHEMBL148319
Peroxisome proliferator-activated receptor-α/Peroxisome proliferator-activated receptor alpha in Human [ChEMBL: CHEMBL239] [GtoPdb: 593] [UniProtKB: Q07869] There should be some charts here, you may need to enable JavaScript!
Peroxisome proliferator-activated receptor-β/δ/Peroxisome proliferator-activated receptor delta in Human [ChEMBL: CHEMBL3979] [GtoPdb: 594] [UniProtKB: Q03181] There should be some charts here, you may need to enable JavaScript!
Peroxisome proliferator-activated receptor-γ/Peroxisome proliferator-activated receptor gamma in Human [ChEMBL: CHEMBL235] [GtoPdb: 595] [UniProtKB: P37231] There should be some charts here, you may need to enable JavaScript!
DP1 receptor in Human [GtoPdb: 338] [UniProtKB: Q13258] There should be some charts here, you may need to enable JavaScript!
EP1 receptor in Human [GtoPdb: 340] [UniProtKB: P34995] There should be some charts here, you may need to enable JavaScript!
EP2 receptor in Human [GtoPdb: 341] [UniProtKB: P43116] EP2 receptor in Mouse [GtoPdb: 341] [UniProtKB: Q62053] There should be some charts here, you may need to enable JavaScript!
EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115] EP3 receptor in Mouse [GtoPdb: 342] [UniProtKB: P30557] There should be some charts here, you may need to enable JavaScript!
EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408] EP4 receptor in Mouse [GtoPdb: 343] [UniProtKB: P32240] There should be some charts here, you may need to enable JavaScript!
FP receptor in Human [GtoPdb: 344] [UniProtKB: P43088] FP receptor in Mouse [GtoPdb: 344] [UniProtKB: P43117] There should be some charts here, you may need to enable JavaScript!
IP receptor in Human [GtoPdb: 345] [UniProtKB: P43119] IP receptor in Mouse [GtoPdb: 345] [UniProtKB: P43252] There should be some charts here, you may need to enable JavaScript!
TP receptor in Human [GtoPdb: 346] [UniProtKB: P21731] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Peroxisome proliferator-activated receptor-α/Peroxisome proliferator-activated receptor alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL239] [GtoPdb: 593] [UniProtKB: Q07869]
ChEMBL	In vitro transactivation of human Peroxisome proliferator activated receptor alpha (hPPARalpha)	B	6.02	pEC50	960	nM	EC50	J Med Chem (2003) 46: 4883-4894 [PMID:14584939]
ChEMBL	In vitro transactivation using receptor transactivation assay against hPPAR alpha	F	6.47	pEC50	340	nM	EC50	J Med Chem (2002) 45: 789-804 [PMID:11831892]
Peroxisome proliferator-activated receptor-β/δ/Peroxisome proliferator-activated receptor delta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3979] [GtoPdb: 594] [UniProtKB: Q03181]
ChEMBL	In vitro transcriptional activation of hPPAR delta	F	5.62	pEC50	2410	nM	EC50	J Med Chem (2002) 45: 789-804 [PMID:11831892]
ChEMBL	In vitro transactivation of human Peroxisome proliferator activated receptor delta (hPPARdelta)	B	5.73	pEC50	1880	nM	EC50	J Med Chem (2003) 46: 4883-4894 [PMID:14584939]
Peroxisome proliferator-activated receptor-γ/Peroxisome proliferator-activated receptor gamma in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL235] [GtoPdb: 595] [UniProtKB: P37231]
ChEMBL	In vitro transactivation of human Peroxisome proliferator activated receptor gamma	B	5.1	pEC50	7910	nM	EC50	J Med Chem (2003) 46: 4883-4894 [PMID:14584939]
DP1 receptor in Human [GtoPdb: 338] [UniProtKB: Q13258]
GtoPdb	-	-	6.9	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP1 receptor in Human [GtoPdb: 340] [UniProtKB: P34995]
GtoPdb	-	-	7.6	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP2 receptor in Human [GtoPdb: 341] [UniProtKB: P43116]
GtoPdb	-	-	6	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP2 receptor in Mouse [GtoPdb: 341] [UniProtKB: Q62053]
GtoPdb	-	-	5.8	pKi	-	-	-	Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115]
GtoPdb	-	-	7.85	pKi	14	nM	Ki	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP3 receptor in Mouse [GtoPdb: 342] [UniProtKB: P30557]
GtoPdb	-	-	7.51	pKi	31	nM	Ki	Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408]
GtoPdb	-	-	6.5	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP4 receptor in Mouse [GtoPdb: 343] [UniProtKB: P32240]
GtoPdb	-	-	5.6	pKi	-	-	-	Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
FP receptor in Human [GtoPdb: 344] [UniProtKB: P43088]
GtoPdb	-	-	6.5	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
FP receptor in Mouse [GtoPdb: 344] [UniProtKB: P43117]
GtoPdb	-	-	5.9	pKi	-	-	-	Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
IP receptor in Human [GtoPdb: 345] [UniProtKB: P43119]
GtoPdb	-	-	6.6	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
IP receptor in Mouse [GtoPdb: 345] [UniProtKB: P43252]
GtoPdb	-	-	7	pKi	-	-	-	Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
TP receptor in Human [GtoPdb: 346] [UniProtKB: P21731]
GtoPdb	-	-	4.7	pKi	-	-	-	Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]