compound 19 [PMID: 33979649] [Ligand Id: 11543] activity data from GtoPdb

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  • CoV Papain-like protease in SARS-CoV-2 [GtoPdb: 3132] [UniProtKB: P0DTC1]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CoV Papain-like protease in SARS-CoV-2 [GtoPdb: 3132] [UniProtKB: P0DTC1]
GtoPdb Binding affinity by surface plasma resonance (SPR) - 5.59 pKd 2600 nM Kd Cell Chem Biol (2021) 28: 855-865.e9 [PMID:33979649]
GtoPdb Inhibition of PL-pro-mediated substrate cleavage in vitro - 6.36 pIC50 440 nM IC50 Cell Chem Biol (2021) 28: 855-865.e9 [PMID:33979649]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.